UHMK1通过增强IL-6/STAT3信号来帮助结直肠癌细胞的增殖和化学抗性

[[Moleculin Biotech, Inc.] Moleculin Biotech, Inc. announced that it has received approval from the United Kingdom’s MHRA to proceed with a first-in-human Phase Ia study to evaluate the safety and pharmacokinetics of WP1122 in healthy volunteers for the treatment of COVID-19.

[Elife]研究人员用源自JMML患者和新型NS斑马鱼模型的SHP2突变探索了造血干和祖细胞的转录组。

[JCI Insight]作者证明，MEF2C表达升高会阻止Notch诱导的T细胞分化，同时促进B-Linege程序。